Explain Why Different Routes Affect the Dose of Medication Given

This route is mainly used for diagnostic tests and it is also used for injecting BCG vaccine. This route avoids nausea or vomiting.

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Hence the different route of administration will affect the dose give since we have to consider first-pass Drug metabolism occur in the liver.

. Transdermal Route Oral Route. Describe the effect of the blood-brain barrier to the distribution of medication. When you take drugs by mouth and drug is absorbed from the GI tract.

Some need to b swallowed some injected and yet others administered by compress or suppository. This route is used to inject small amount of drug 2 ml or lesser. Common routes of administration include oral rectal inhalation nasal and topical.

The transdermal route is commonly referred to as the patch because the medication is contained in a patch that is absorbed through the skin. Explain why different routes affect the dose of medication given. Occursthrough binding or chemical interactionthe concentration of the drug at the site of action controls the effect.

For example food in the. The optimal dosage is the dosage that gives the desired effect with minimum side effects. Routes of drug administration 1.

Drugs administered through this route must be highly lipophilic. See answer 1 Best Answer. This will be people that have asthma and inhaling means that the medicine will be able to get to the area of the body where it is most needed quicker than swallowing medication.

Medications are effective just when they reach their site of action so different routes of drug administration are used to produce systemic effects they provide significant advantages and have some disadvantages that depend on the requirement and way of drug administration. Topical routes of administration also affect dose because it is not intended to have a systemic effect but only a local effect. Protein binding both in the plasma and in the tissues will markedly affect this distribution.

Explain why different routes affect the dose of medication given are medications that are administrated in an inactive form and change into the active form during the metabolic process. Most drugs must pass through the liver which is the primary site for drug metabolism. Although solid-dose forms such as tablets and capsules have a high degree of drug stability and provide accurate dosage the oral route is problematic because of the unpredictable nature of gastrointestinal absorption.

This route can induce pain during the injection. There are many factors taken into consideration when deciding a dose of drug - including age of the patient weight sex ethnicity. This is the most frequently used route of drug administration and is the most convenient and cost-effective.

The three main parenteral routes of drug administration are IV IM and SC and in all cases administration is usually via a hollow needle. A drug given parenterally is one given by a route other than the mouth topical dosage forms are considered separately. Drugs in solid forms such as suppositories or in liquid forms such as enema are given by this route.

Helpful 0. However free drug concentrations are generally relieved to be the effective determinant in drug therapy. The design of the dosage forms requires a deep knowledge of.

Tablets Capsules Liquids Mixtures. The mouth route is the most commonly used route of drug administration due to the ease in which the drugs can be taken. Injectable preparations are usually sterile solutions or suspensions of drug in water or other suitable physiologically.

Small intestine has larger surface area and long residence time. The relationship between the drug dose regardless of route used and the drug concentration at the cellular level is. Little absorption occur in stomach because of small area and short residence time.

That is why more technically the oral route is part of the enteral route with enteral referring to the intestines these drugs eventually reach. Drugs may have local or systemic actions after absorption. Why are medications given via different routes.

Drug distribution in the patient will depend on the blood flow to various sites in the body as well as the partition coefficient of the drug between the blood and the distributive organs. 5explain why a provider may. The route of administration is the way the dosage form is given.

Protein binding both in the plasma and in the tissues will markedly affect this distribution. This route is risky as once the drug is given it cannot be retrieved back or stopped easily. These considerations are important on the biopharmaceutical production and evaluation of drugs.

Examples of topical drugs include antifungals antibiotics eyedrops creams ointments etc. Absorption via this route is slow but conducive to producing long-lasting effects. However response to concentration may be complex and is often nonlinear.

Also frequent injections can cause wounds or abscesses. A list of commonly used routes of drug administration can be found below along with useful information about dosage and abbreviations. Subcutaneous injections are made into the loose subcutaneous tissue under the skin.

3describe why medications are limited when a female is breastfeeding her baby. Oral medication includes. One needs a syringe cotton sterilizing agent before administering the injection.

Inhalation For people who have difficulty with respiratory issues they will often inhale medication. 4describe six factors that influence drug action. The route of drug administration is the route by which a drug is delivered or.

So this adds up the cost. Orally administered drugs absorbed mainly from small intestine. This route is mostly used in old patients.

So the dose needed would not be as great as compared to when it is needed for use systemically. Routes of Drug Administration 1. Drug absorption is slower and drug action is longer.

This route is preferred in unconscious or uncooperative patients. Describe why only limited medications can be given to a woman who is pregnant. The amount of drug is small and absorption is slow.

Special slow-release matrices in some transdermal patches can maintain. Medications are given by the way they work best. What are most drugs metabolism occurwhat populations have issues metabolizing medications and are at risk for toxicity.

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